This article, adapted from Edgeware: Lessons From Complexity Science for Health Care Leaders, by Brenda Zimmerman, Curt Lindberg, and Paul Plsek, proposes some principles of management that are consistent with an understanding of organizations as CASs. In the spirit of the subject matter, there is nothing sacred or permanent about this list. However, these principles do begin to give us a new way of thinking about and approaching our roles as leaders in organizations.